The problem with grapefruit, as well as Seville oranges, pomelos and limes, is that some substances found in the juice inhibit an enzyme found in the intestines and liver that aids in metabolizing some drugs. The result of this inhibition is that you may end up with a higher level of the active ingredient of the drug iin your bloodstream. This can lead to serious problems such as acute kidney failure, heart problems, kidney failure, trouble breathing and gastrointestinal bleeding.
This interaction occurs quickly and can last 24 hours or longer. The effects vary from person to person, but older people are at higher risk. The danger is also greater for drugs that have little forgiveness if the dose is off by even the slightest amount.
The bottom line if you take a prescription medication is to check with your health care professional. before consuming grapefruit or other juices mentioned above. If there is an interaction and if you want to stay out of trouble stop drinking grapefruit juice. Try orange or tangerine juice instead.
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